Rinne Kudo, who is studying abroad in England, sees her classmate kidnapped by Yoko Minato right in front of her. Rinne returns to Japan with Sophia's guidance, who is investigating a series of female kidnappings, and decides to investigate the case with Girls Remix. They head to the scene of the crime with Reika Shindai to investigate a case suspected to involve an alchemist. At that moment, Yoko appears again and attacks them, but a woman who looks like Clotho appears and fights Yoko. Will Rinne be able to solve the case and save her classmates?!